Dr. Gregory Mathien was born in Buffalo, New York, and attended State University of New York in Syracuse for both his undergraduate and medical degrees. He remained in Syracuse to complete his surgical internship and orthopaedic surgery residency.

In 1991, Dr. Mathien came to Knoxville for the Sports Medicine Fellowship under the direction of Dr. William T. Youmans. During his fellowship, KOC recruited him to remain as a KOC surgeon and help expand the KOC sports medicine program, enhancing the care of injured athletes. This has evolved into an extensive program placing certified athletic trainers in Knox County high schools. In developing this program he received the Tennessee Interscholastic Athletic Administrators Association Distinguished Service Award in 2011.

Dr. Mathien currently serves as the Senior Team Orthopaedic Surgeon for the University of Tennessee athletic programs. The University of Tennessee Lettermen’s “T” Club has given him Honorary Membership status. 

Dr. Mathien has served as a consultant for the Tennessee Smokies, the Knoxville Ice Bears and Lincoln Memorial University athletics. He has also operated on and cared for many Olympic medalists and professional athletes. He plays an active role in national sports medicine research, including the Multicenter ACL Revision Study.

Dr. Mathien is board certified by the American Board of Orthopaedic Surgery in sports medicine and is a member of the American Orthopaedic Society for Sports Medicine and the American Academy of Orthopaedic Surgeons.

He and his wife, Clara, live in Knoxville. They have two children, Zachary and Rebecca, along with their Labrador retrievers. They are active in their church and community activities.