Our Physicians

John M. Ambrosia, M.D.

Hand Surgery Specialist


Dr. John Ambrosia was born in Chicago. He attended Loyola University Chicago and Loyola University - Stritch School of Medicine. After completing his orthopaedic surgery residency at Indiana University Medical Center in Indianapolis, he went on to a fellowship in hand surgery at the Mayo Clinic in Rochester, Minnesota. 

Dr. Ambrosia joined Knoxville Orthopaedic Clinic in 1986. He enjoys the subspecialty nature of KOC, which allows him to focus his attention and efforts on problems, injuries, and diseases of the hand and wrist.

Dr. Ambrosia has been selected by his peers to the "Best Doctors in America” and Cityview Magazine's "Top Docs." He is board certified by the American Board of Orthopaedic Surgery and has earned a Certificate for Added Qualifications for Surgery of the Hand. He is a member of the American Society for Surgery of the Hand and the American Academy of Orthopaedic Surgeons.

Dr. Ambrosia has been married to his wife Lou for more than 25 years and they have three children. He enjoys gardening and hiking in his spare time.



Contact Information

Office Info KOC: 865-558-4400
Appointments: 865-558-4444
Office Location

Old Weisgarber Road
Fort Sanders West
North Knoxville Medical Center Physicians Plaza

Administrative Assistant

865-450-1231 or internal ext 4231


865-450-1220 or internal ext 4003


Dr. Ambrosia's Educational Links



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What patients say about Dr. Ambrosia

  • Thanks to my care at KOC, I am getting back to full range of motion, strength, and grip. Dr. Ambrosia is a very caring person with the most wonderful bedside manner I have ever received from a surgeon. He explained his very conservative approach, indicating a desire to avoid elbow replacement surgery and the associated complications. I am so thankful that Dr. Ambrosia was put in my path to help me on this difficult journey back to health.
    – Lisa, Knoxville
  • Thanks to my care at KOC, I can use my thumb without pain or it constantly clicking in and out of place. The relief was almost instant.

    Dr. John Ambrosia was very patient and understanding with me being 'chicken' when it comes to needles. He took time to explain everything that would happen and didn't make false promises about the pain. It did hurt, but not long and the results were well worth it. I wish I had not waited as long as I did to go get it checked out. :)
    – Norma, Lenoir City


  • B.S., Loyola University, Chicago, Illinois, 1977
  • M.D., Loyola - Stritch School of Medicine, Maywood, Illinois, 1980


  • St. Vincent Hospital, Indianapolis, Indiana, 1981


  • Indiana University Medical Center, Indianapolis, Indiana, 1985


  • Hand Surgery, Mayo Clinic, Rochester, Minnesota, 1986

Began Practice At KOC

  • 1986

Board Certification

  • American Board of Orthopaedic Surgery, 1988
  • American Board of Orthopaedic Surgery, Certificate of Added Qualification in Hand Surgery, 1996

Orthopaedic Specialty

  • Hand and Upper Extremity Surgery